Modern Therapeutic Pharmacology: Precision Therapeutics Across Organ Systems
Keywords:
system-based pharmacology, precision therapeutics, pharmacogenomics, molecular pharmacology, clinical pharmacogeneticsSynopsis
This book provides a comprehensive and authoritative exploration of modern pharmacology, blending classical foundations with emerging concepts in precision therapeutics and system-based approaches to drug development and clinical application. It is structured to guide readers through all major organ systems, including cardiovascular, central nervous, respiratory, endocrine, renal, gastrointestinal, hematologic, dermatologic, ophthalmic, musculoskeletal, reproductive, and urogenital systems, while integrating both well-established drug classes and novel biologics, RNA-based medicines, and advanced delivery platforms. Emphasis is placed on the interconnectedness of physiological systems and molecular signaling networks, the evolving role of pharmacokinetics and pharmacodynamics, and the incorporation of systems biology into therapeutic decision-making. The book delves into the transformative impact of pharmacogenomics, omics technologies, and biomarker-guided therapy, while also highlighting the growing influence of artificial intelligence, digital health innovations, and clinical decision-support systems in optimizing treatment outcomes. It further addresses contemporary pharmacological challenges including polypharmacy, drug-drug interactions, regulatory considerations, and the specific needs of pediatric and geriatric populations. Looking ahead, the text explores future directions in pharmacology such as gene editing, cell-based therapies, exosome-based delivery, and 3D-printed pharmaceuticals. Designed for clinicians, researchers, educators, and advanced students, this volume serves as a definitive academic reference, offering both depth and practicality for those engaged in the advancement of personalized, precision-based medical care.
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